May 18, 2016
May 26th 3-4pm, Biostatistics Visiting Faculty Seminar
VISITING FACULTY SEMINAR
May 26, 2016 at
3:00p.m. – 4:00p.m.
Hui Zhang, Ph.D.
Assistant Member, Department of Biostatistics – St. Jude Children’s Research Hospital
Major Challenges in Count Data Analysis
Count data plays an important role in biomedical and clinical research, especially nowadays with the rapid progress in next generation sequencing. However, using routine statistical model to analyze counts, such as Poisson model, often results in biased or even misleading conclusions. Primary challenges when applying Poisson model to count data include overdispersion and zero-inflation, which are commonly encountered in practice. In addition, the repeated measures and incomplete observations in modern clinical trials add to complexity. This talk will review these challenges in count data analysis and recent methodology progress made by the speaker.