UAMS.EDU

Courses Offered

PBHL 5113: Environmental and Occupational Health This course is intended to provide a detailed overview of the fields of environmental and occupational health, with an emphasis on the practical aspects of the recognition, evaluation and control of chemical, physical and biological hazards, including basic quantitative assessment of these hazards. Additional topics include significant legal and historical influences as well as currently important issues in the fields.

PBHL 5043/OEHM 5043: Occupational and Environmental Hazard ControlDetailed study of the principles and practices involved in the control of environmental health hazards, with particular attention to occupational hazards. Topics covered will include ventilation for airborne contaminants, respiratory protection, electrical and mechanical safety methods, and the control of hazards from noise, vibration, radiation, heat, biohazards, and chemical hazards.

PBHL 5063/OEHM 5063: Toxicology in Public Health: Considers the harmful effects of chemical agents, naturally occurring or synthetically produced, on animals and humans. Emphasis placed on general principles of the mechanism of action, the importance of intraspecies differences, as well as mutagenesis, teratogenesis, and carcinogenesis as manifestations of toxicity. Prerequisite: PBHL 5113/OEHM 5023.

PBHL 5073/OEHM 5073: Regulation in Environmental HealthOperational and conceptual toxicology with the statutory basis for and aspects of governmental regulation of environmental hazards to public health. Provides potential industrial hygienists with a better understanding of the relationships that exist between scientific aspects of toxicology and their application through the statutory framework and related governmental regulations in the public health arena. (Same as INTX 5073)

PBHL 5153/OEHM 5153: Environmental and Industrial Biological HazardsBiological hazards in the workplace and the natural environment. Covers human perturbations of the natural environment, contamination and treatment of water resources, biohazardous agents in occupational environments, and prevention, surveillance and regulations regarding biological hazards.Prerequisites: Eight hours of biology coursework, or permission of the instructor.

PBHL 5263/OEHM 5263: Environmental Exposure AssessmentQuantitative introduction to the generation, propagation, measurement, and evaluation of air contaminants (including aerosols, gases and vapors). Principles of sample collection and analysis, direct measurement, and statistical analysis and interpretation of results are covered. Applications studied include monitoring and modeling of industrial, community, transportation, and indoor environments and sources.

OEHM/PBHL 9043: Environmental and Occupational Health PolicyThis course covers issues relevant to policy decisions in the environmental and occupational health field, including such topics as strategies for the assessment, management and communication of risk, alternative approaches to environmental regulation and compliance, ethical questions in environmental and occupational health, and similar contemporary concerns. Prerequisites: PBHL 5113 and 5023.

OEHM 509V: Advanced Toxicology: This advanced course is a modular course consisting of several interdisciplinary areas. Those areas of study include developmental, occupational, and environmental toxicology. Will provide students with in-depth information concerning the use of basic medical sciences to assess chemical and drug-induced toxicity and to evaluate public health problems. (Same as INTX 509V.) Prerequisite: OEHM 5023.

OEHM 5033: General Principles of Pharmacology and Toxicology: The time course and spatial distribution of drug levels in various body compartments are analyzed using the fundamentals of transport phenomena, reaction kinetics, and process dynamics. (Same as INTX 5033)

OEHM 5051: Professional Communications and Ethics Seminar: An overview of the process of developing investigation questions, methods, evaluations, and publications. Also, various faculty will lead discussions concerning ethical conduct related to professional practice, scientific publishing, and research. An oral presentation reviewing recent peer-reviewed research on a topic of interest to the student will be required.

OEHM 5082: Introduction to Oncology: Lectures, assigned readings and examinations regarding the molecular basis of carcinogenesis. Emphasis is placed on in-depth study of chemical carcinogenesis and factors mediating the oncogenic response. The role of host-factors and techniques for assessment of carcinogenic risk are presented.

PBHL 511V: Special Topics in Occupational and Environmental Health: Gives in-depth treatment to topics of current importance and to specialized subjects not covered in general courses. Each topic will be a narrowly defined aspect of occupational or environmental health.

OEHM 6013: Principles of Food and Drug Regulations: This class explores how developing science and changes in commerce have influenced the basic laws, regulations and policies used by the United States Food and Drug Administration to insure the safety of medical products, food and cosmetics. Also, the impact of FDA’s regulations and policy in protecting consumers and promoting public health is examined. The course will focus on the use of toxicology as the scientific discipline that  forms the foundation for actions taken by the Food and Drug Administration. The overall goal is for students to gain a working knowledge of how laws and regulations impact on Regulatory Sciences and public health. The course incorporates lecture presentations, classroom discussions of case studies and writing of critiques of current issues before the agency.

OEHM 6023: Methods in Risk Assessment and Management: The course reviews the utilization of risk assessment by Federal Government regulatory agencies with emphasis on the US Food and Drug Administration. The course describes basic principles and provides hands-on training with  methods used to quantify or predict human risk. Emphasis will be placed on dose-response assessments and topics relevant to estimating human health risk from drugs, food additives, cosmetics and other regulated products. The course is organized to provide a systematic approach to current and emerging assessment practices. The course includes the application of the latest methods for describing human health risks from drugs and other chemicals. Topics include the utilization of current in vitro and in vivo pre-clinical testing methods, scientific principles underlying extrapolation from animal toxicity testing to the assessment. The use of post approval data to estimate risk is demonstrated. The course will utilize readings, classroom lectures and presentations, classroom discussions/demonstrations, written critiques, and presentations of current issues in risk assessment.

OEHM 6033: Design and Management of Clinical Trials:

This course examines the design and conduct of clinical trials from the perspectives of the investigator, sponsor, and regulators. Basic principles of study design is reviewed and applied. Students will gain experience developing a clinical trial protocol in a team-based environment that will simulate project development in the pharmaceutical industry. Elements of study conduct is explored from multiple perspectives including study sites, sponsors, and regulatory agencies. Contemporary issues in study design and management is considered. Problem solving, case studies, and group projects, are used to provide a participation-based learning experience. Many of the topics are presented by guest lecturers who are experts in their subject matter.

PHSC 6043: Good Regulatory Practices:

This course examines the FDA and ICH regulations on good manufacturing,  laboratory, and clinical practices. The meaning of these regulations, the  globalization of practices, and the roles and responsibilities of various professionals implementing these regulations is addressed. Special emphasis is on detailed coverage of the process for the assembly and submission of an IND or NDA and the function of the regulatory affairs department in a pharmaceutical company and data quality issues required for regulatory decision-making.

PBHL 6023: Climate Change and Public Health

Climate change is an exceptional global environmental crisis primarily driven by anthropogenic activities with adverse consequences on ecological and life systems. This course will provide students an overview of the driving forces and mechanics of climate change and comprehensive analysis of the implications on Earth’s natural/human ecosystems and health in a local, regional, and global scale. The concepts, approaches and uncertainties of methods applied to assess and monitor the health impacts of climate change will be presented and specific disease cases will be discussed. Lastly, ongoing efforts to cope/adapt, mitigate or reduce the impacts and the mechanisms to develop these tools will be examined.

Biology of Public Health Courses

PBHL 5011: Biology for Public Health: Infectious Disease: Biology for Public Health is an introductory course which provides a foundation of biology concepts necessary for the practice of public health. The lectures in this course will focus on the biology basics
related to infectious disease including an overview of infectious disease epidemiology; the different types of pathogens; the immune system and response to pathogens; treatment, prevention, and control of infectious disease; and the role humans play in the evolution of infectious diseases. Each lecture series will relate covered biological concepts back to examples of common infectious diseases affecting US and worldwide populations. The course will also assist students in their preparations for the National Board
of Public Health Examiners’ (NBPHE) Certification Exam.

PBHL 5211: Biology for Public Health: Chronic Disease: Biology for Public Health is an introductory course which provides a foundation of biology concepts necessary for the practice of public health. The lectures in this course will focus on the biology basics
related to chronic disease including an overview of Mendelian genetics; cardiovascular disease; diabetes; respiratory disease; as well as the biology of addiction and mental illness. Each lecture series will relate covered biological concepts back to major issues surrounding chronic diseases affecting US and worldwide populations. The course will also assist students in their preparations for the National Board of Public Health Examiners’ (NBPHE) Certification Exam

PBHL 5311: Biology for Public Health: Current Topics in Public Health: Biology for Public Health is an introductory course which provides a foundation of biology concepts necessary for the practice of public health. The lectures in this course will focus on the biology basics related to current topics in public health including an overview of the biology of growth and development, biology of aging, biology of cancer, micronutrients and dietary supplements, and obesity. Each lecture series will relate covered biological concepts back to major issues surrounding current diseases affecting US and worldwide populations. The course will also assist students in their preparations for the National Board of Public Health Examiners’ (NBPHE) Certification Exam.