May 18, 2016

May 26th 3-4pm, Biostatistics Visiting Faculty Seminar


May 26, 2016 at
3:00p.m. – 4:00p.m.
COPH 2280

Speaker information:
Hui Zhang, Ph.D.
Assistant Member, Department of Biostatistics – St. Jude Children’s Research Hospital
Memphis, TN

Major Challenges in Count Data Analysis

Count data plays an important role in biomedical and clinical research, especially nowadays with the rapid progress in next generation sequencing. However, using routine statistical model to analyze counts, such as Poisson model, often results in biased or even misleading conclusions. Primary challenges when applying Poisson model to count data include overdispersion and zero-inflation, which are commonly encountered in practice. In addition, the repeated measures and incomplete observations in modern clinical trials add to complexity. This talk will review these challenges in count data analysis and recent methodology progress made by the speaker.