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Fay W. Boozman College of Public Health: Arkansas Center for Excellence in Birth Defects Research and Prevention

Peer-Reviewed Center Publications

National Birth Defects Prevention Network Surveillance Data

Peer-Reviewed Publications from 2017-2021

  • Desrosiers, T. A., Siega-Riz, A. M., Mosley, B. S., & Meyer, R. E. (2018). Low carbohydrate diets may increase risk of neural tube defects. Birth Defects Res. doi:10.1002/bdr2.1198
  • Nembhard, W. N., Tang, X., Li, J., MacLeod, S. L., Levy, J., Schaefer, G. B., & Hobbs, C. A. (2018). A parent-of-origin analysis of paternal genetic variants and increased risk of conotruncal heart defects. Am J Med Genet A, 176(3), 609-617. doi:10.1002/ajmg.a.38611
  • Kim, J., Swartz, M. D., Langlois, P. H., Romitti, P. A., Weyer, P., Mitchell, L. E., Agopian, A. J. (2017). Estimated Maternal Pesticide Exposure from Drinking Water and Heart Defects in Offspring. Int J Environ Res Public Health, 14(8). doi:10.3390/ijerph14080889
  • Lara, D. A., Ethen, M. K., Canfield, M. A., Nembhard, W. N., & Morris, S. A. (2017). A population-based analysis of mortality in patients with Turner syndrome and hypoplastic left heart syndrome using the Texas Birth Defects Registry. Congenit Heart Dis, 12(1), 105-112. doi:10.1111/chd.12413
  • Lopez, K. N., Nembhard, W. N., Wang, Y., Liu, G., Kucik, J. E., Copeland, G., Canfield, M. (2018). Birth defect survival for Hispanic subgroups. Birth Defects Res, 110(4), 352-363. doi:10.1002/bdr2.1157
  • Lupo, P. J., Isenburg, J. L., Salemi, J. L., Mai, C. T., Liberman, R. F., Canfield, M. A., Kirby, R. S. (2017). Population-based birth defects data in the United States, 2010-2014: A focus on gastrointestinal defects. Birth Defects Res, 109(18), 1504-1514. doi:10.1002/bdr2.1145
  • Nembhard, W. N., Tang, X., Hu, Z., MacLeod, S., Stowe, Z., & Webber, D. (2017). Maternal and infant genetic variants, maternal periconceptional use of selective serotonin reuptake inhibitors, and risk of congenital heart defects in offspring: population based study. BMJ, 356, j832. doi:10.1136/bmj.j832
  • Padiyath, A., Makil, E. S., Braley, K. T., Bolin, E. H., Tang, X., Gossett, J. M., & Collins, R. T., 2nd. (2017). Frequency of Development of Aortic Valve Disease in Unrepaired Perimembranous Ventricular Septal Defects. Am J Cardiol, 119(10), 1670-1674. doi:10.1016/j.amjcard.2017.02.004
  • Prodhan, P., Agarwal, A., ElHassan, N. O., Bolin, E. H., Beam, B., Garcia, X., Tang, X. (2017). Tracheostomy Among Infants With Hypoplastic Left Heart Syndrome Undergoing Cardiac Operations: A Multicenter Analysis. Ann Thorac Surg, 103(4), 1308-1314. doi:10.1016/j.athoracsur.2016.09.016
  • Rabie, N. Z., Sandlin, A. T., Barber, K. A., Ounpraseuth, S., Nembhard, W., Magann, E. F., & Lowery, C. (2017). Teleultrasound: How Accurate Are We? J Ultrasound Med, 36(11), 2329-2335. doi:10.1002/jum.14304
  • Shinkawa, T., Holloway, J., Tang, X., Gossett, J. M., & Imamura, M. (2017). A ferromagnetic surgical system reduces phrenic nerve injury in redo congenital cardiac surgery. Interact Cardiovasc Thorac Surg, 24(5), 802-803. doi:10.1093/icvts/ivw444
  • Shinkawa, T., Chipman, C., Holloway, J., Tang, X., Gossett, J. M., & Imamura, M. (2017). Single center experience of aortic bypass graft for aortic arch obstruction in children. Heart Vessels, 32(1), 76-82. doi:10.1007/s00380-016-0842-x
  • St Louis, A. M., Kim, K., Browne, M. L., Liu, G., Liberman, R. F., Nembhard, W. N., Kirby, R. S. (2017). Prevalence trends of selected major birth defects: A multi-state population-based retrospective study, United States, 1999 to 2007. Birth Defects Res, 109(18), 1442-1450. doi:10.1002/bdr2.1113
  • Stingone, J. A., Luben, T. J., Carmichael, S. L., Aylsworth, A. S., Botto, L. D., Correa, A., Olshan, A. F. (2017). Maternal Exposure to Nitrogen Dioxide, Intake of Methyl Nutrients, and Congenital Heart Defects in Offspring. Am J Epidemiol, 186(6), 719-729. doi:10.1093/aje/kwx139
  • Rabie, N. , Sandlin, A., Ounpraseuth, S., Nembhard, W., Lowery, C., San Miguel, K., & Magann, E. (2018). Teleultrasound: A validation study. Am U OBGYN. 218(1), 264-265. doi.org/10.1016/j.ajog.2017.10.372
  • Tang, X., Eberhart, J.K., Cleves, M.A. et al.PDGFRA gene, maternal binge drinking and obstructive heart defects. Sci Rep 8, 11083 (2018). doi:10.1038/s41598-018-29160-9
  • Nembhard WN, Tang X, Li J, et al. A parent-of-origin analysis of paternal genetic variants and increased risk of conotruncal heart defects. Am J Med Genet A. 2018;176(3):609-617. doi:10.1002/ajmg.a.38611
  • Jenkins MM, Almli LM, Pangilinan F, et al. Exome sequencing of family trios from the National Birth Defects Prevention Study: Tapping into a rich resource of genetic and environmental data. Birth Defects Res. 2019;111(20):1618-1632. doi:10.1002/bdr2.1554
  • Lou XY, Hou TT, Liu SY, et al. Innovative approach to identify multigenomic and environmental interactions associated with birth defects in family-based hybrid designs. Genet Epidemiol. 2021;45(2):171-189. doi:10.1002/gepi.22363
  • Lupo PJ, Schraw JM, Desrosiers TA, et al. Association Between Birth Defects and Cancer Risk Among Children and Adolescents in a Population-Based Assessment of 10 Million Live Births. JAMA Oncol.2019;5(8):1150–1158. doi:10.1001/jamaoncol.2019.1215
  • Nembhard WN, Ayers BL, Collins RT, et al. Adverse Pregnancy and Neonatal Outcomes Among Marshallese Women Living in the United States. Matern Child Health J. 2019;23(11):1525-1535. doi:10.1007/s10995-019-02775-8
  • Bakker MK, Bergman JEH, Krikov S, et alPrenatal diagnosis and prevalence of critical congenital heart defects: an international retrospective cohort studyBMJ Open 2019;9:e028139. doi: 10.1136/bmjopen-2018-028139
  • Nembhard WN, McElfish PA, Ayers B, et al. Nuclear radiation and prevalence of structural birth defects among infants born to women from the Marshall Islands. Birth Defects Res. 2019;111(16):1192-1204. doi:10.1002/bdr2.1551
  • Goel N, Morris JK, Tucker D, et al. Trisomy 13 and 18-Prevalence and mortality-A multi-registry population based analysis. Am J Med Genet A. 2019;179(12):2382-2392. doi:10.1002/ajmg.a.61365
  • Farr SL, Klewer SE, Nembhard WN, et al. Rationale and design of CH STRONG: Congenital Heart Survey To Recognize Outcomes, Needs, and well-beinG. Am Heart J. 2020;221:106-113. doi:10.1016/j.ahj.2019.12.021
  • Patel J, Nembhard WN, Politis MD, et al. Maternal occupational exposure to polycyclic aromatic hydrocarbons and the risk of isolated congenital heart defects among offspring. Environ Res. 2020;186:109550. doi:10.1016/j.envres.2020.109550
  • Ramseyer AM, Whittington JR, Magann EF, Warford B, Ounpraseuth S, Nembhard WN. Hospital Annual Delivery Volume and Presence of Graduate Medical Education Influence Mode of Delivery after Stillbirth. South Med J. 2020;113(12):623-628. doi:10.14423/SMJ.0000000000001180
  • Nembhard WN, Bergman JEH, Politis MD, et al. A multi-country study of prevalence and early childhood mortality among children with omphalocele. Birth Defects Res. 2020;112(20):1787-1801. doi:10.1002/bdr2.1822
  • Patel J, Schraw JM, Lupo PJ, Mian A, Nembhard WN. Cancer Risk by Attained Age among Children with Birth Defects in Arkansas. Cancer Epidemiol. 2020;68:101796. doi:10.1016/j.canep.2020.101796
  • ELHassan NO, Young SG, Gokun Y, Wan F, Nembhard WN. Trends in prevalence and spatiotemporal distribution of gastroschisis in Arkansas, 1998-2015. Birth Defects Res. 2020;112(18):1484-1494. doi:10.1002/bdr2.1772
  • Politis MD, Bermejo-Sánchez E, Canfield MA, et al. Prevalence and mortality in children with congenital diaphragmatic hernia: a multicountry study. Ann Epidemiol. 2021;56:61-69.e3. doi:10.1016/j.annepidem.2020.11.007
  • Collins RT 2nd, Yang W, Carmichael SL, et al. Maternal dietary fat intake and the risk of congenital heart defects in offspring. Pediatr Res. 2020;88(5):804-809. doi:10.1038/s41390-020-0813-x
  • Marcotte EL, Schraw JM, Desrosiers TA, et al. Male Sex and the Risk of Childhood Cancer: The Mediating Effect of Birth Defects. JNCI Cancer Spectr. 2020;4(5):pkaa052. Published 2020 Jun 11. doi:10.1093/jncics/pkaa052
  • Zaganjor I, Luben TJ, Desrosiers TA, et al. Maternal Exposure to Disinfection By-Products and Risk of Hypospadias in the National Birth Defects Prevention Study (2000-2005). Int J Environ Res Public Health. 2020;17(24):9564. Published 2020 Dec 21. doi:10.3390/ijerph17249564
  • Richard MA, Sok P, Canon S, et al. Altered mechanisms of genital development identified through integration of DNA methylation and genomic measures in hypospadias. Sci Rep. 2020;10(1):12715. Published 2020 Jul 29. doi:10.1038/s41598-020-69725-1
  • Schraw JM, Desrosiers TA, Nembhard WN, et al. Cancer diagnostic profile in children with structural birth defects: An assessment in 15,000 childhood cancer cases. Cancer. 2020;126(15):3483-3492. doi:10.1002/cncr.32982
  • Heinke D, Isenburg JL, Stallings EB, et al. Prevalence of structural birth defects among infants with Down syndrome, 2013-2017: A US population-based study. Birth Defects Res. 2021;113(2):189-202. doi:10.1002/bdr2.1854
  • Zaganjor I, Luben TJ, Desrosiers TA, Keil AP, Engel LS, Michalski A, Carmichael SL, Nembhard WN, Shaw G, Reefhuis J, Yazdy MM, Langlois PH, Feldkamp ML, Romitti PA, Olshan AF and the National Birth Defects Prevention Study. (2020) Maternal exposure to disinfection by-products and risk of hypospadias in the National Birth Defects Prevention Study (2000-2005) Inter J Environ Res Pub Health 2020 Dec 21;17(24):9564. doi: 10.3390/ijerph17249564
  • Oster ME, Riser AP, Andrews JG, Bolin EH, Galindo MK, Nembhard WN, Rose CE and Farr SL. (2021) Comorbidities among young adults with congenital heart defects: Results from the Congenital Heart Survey To Recognize Outcomes, Needs, and well-beinG (CH STRONG) — Arizona, Arkansas, and Metropolitan Atlanta, 2016–2019. Morbidity and Mortality Weekly Report 2021 Feb 12;70(6):197-201. doi: 10.15585/mmwr.mm7006a3.
  • Benjamin RH, Salemi JL, Canfield MA, Nembhard WN, Ganduglia-Cazaban C and Agopian AJ. (2021) Causes of mortality among infants with birth defects in Texas. Birth Def Res 2021 May 15;113(9):665-675. doi: 10.1002/bdr2.1879. Epub 2021 Feb 15.
  • Patel J, + Bircan E, +Tang X, Orloff M, Hobbs CA, Browne ML, Botto LD, Finnell RH, Jenkins MM, Olshan A, Romitti PA, Shaw GM, Werler M, Li J, Nembhard WN and the National Birth Defects Prevention Study. (2021). Paternal Genetic Variants and Risk of Obstructive Heart Defects: A Parent-of-Origin Approach. PLoS Genetics. 2021 Mar 8;17(3):e1009413. doi: 10.1371/journal.pgen.1009413. eCollection 2021 Mar.
  • Bell JC, Baynam G, Bergman JEH, Bermejo-Sánchez E, Botto LD, Canfield MA, Dastgiri S, Gatt M, Groisman B, Hurtado-Villa P, Kallen K, Khoshnood B, Konrad V, Landau D, Lopez-Camelo JS, Martinez L, Morgan M, Mutchinick OM, Nance AE, Nembhard WN, Pierini A, Rissmann A, Shan X, Sipek A, Szabova E, Tagliabue G, Yevtushok LS, Zarante I, and Nassar N. (2021) Survival of Infants born with Esophageal Atresia among 24 International Birth Defects Surveillance Programs Birth Def Res Birth Defects Res. 2021 Mar 18. doi: 10.1002/bdr2.1891. Online ahead of print.
  • Sanz JH, Anixt J, Bear L, Basken A, Beca J, Marino BS, Mussatto KA, Nembhard WN, A Sadhwani, R Sananes, LS Shekerdemian, E Sood, K Uzark, E Willen, and D Ilardi. (2021) Characterization of Neurodevelopmental and Psychological Outcomes in Congenital Heart Disease: A research agenda and recommendations from the Cardiac Neurodevelopmental Outcome Collaborative. Cardiol Young 2021 Jun 4:1-12. doi: 10.1017/S1047951121002146. Online ahead of print.