Peer-Reviewed Center Publications

National Birth Defects Prevention Network Surveillance Data

Peer-Reviewed Publications from 2013-2018

  • Desrosiers, T. A., Siega-Riz, A. M., Mosley, B. S., & Meyer, R. E. (2018). Low carbohydrate diets may increase risk of neural tube defects. Birth Defects Res. doi:10.1002/bdr2.1198
  • Nembhard, W. N., Tang, X., Li, J., MacLeod, S. L., Levy, J., Schaefer, G. B., & Hobbs, C. A. (2018). A parent-of-origin analysis of paternal genetic variants and increased risk of conotruncal heart defects. Am J Med Genet A, 176(3), 609-617. doi:10.1002/ajmg.a.38611
  • Kim, J., Swartz, M. D., Langlois, P. H., Romitti, P. A., Weyer, P., Mitchell, L. E., Agopian, A. J. (2017). Estimated Maternal Pesticide Exposure from Drinking Water and Heart Defects in Offspring. Int J Environ Res Public Health, 14(8). doi:10.3390/ijerph14080889
  • Lara, D. A., Ethen, M. K., Canfield, M. A., Nembhard, W. N., & Morris, S. A. (2017). A population-based analysis of mortality in patients with Turner syndrome and hypoplastic left heart syndrome using the Texas Birth Defects Registry. Congenit Heart Dis, 12(1), 105-112. doi:10.1111/chd.12413
  • Lopez, K. N., Nembhard, W. N., Wang, Y., Liu, G., Kucik, J. E., Copeland, G., Canfield, M. (2018). Birth defect survival for Hispanic subgroups. Birth Defects Res, 110(4), 352-363. doi:10.1002/bdr2.1157
  • Lupo, P. J., Isenburg, J. L., Salemi, J. L., Mai, C. T., Liberman, R. F., Canfield, M. A., Kirby, R. S. (2017). Population-based birth defects data in the United States, 2010-2014: A focus on gastrointestinal defects. Birth Defects Res, 109(18), 1504-1514. doi:10.1002/bdr2.1145
  • Nembhard, W. N., Tang, X., Hu, Z., MacLeod, S., Stowe, Z., & Webber, D. (2017). Maternal and infant genetic variants, maternal periconceptional use of selective serotonin reuptake inhibitors, and risk of congenital heart defects in offspring: population based study. BMJ, 356, j832. doi:10.1136/bmj.j832
  • Padiyath, A., Makil, E. S., Braley, K. T., Bolin, E. H., Tang, X., Gossett, J. M., & Collins, R. T., 2nd. (2017). Frequency of Development of Aortic Valve Disease in Unrepaired Perimembranous Ventricular Septal Defects. Am J Cardiol, 119(10), 1670-1674. doi:10.1016/j.amjcard.2017.02.004
  • Prodhan, P., Agarwal, A., ElHassan, N. O., Bolin, E. H., Beam, B., Garcia, X., Tang, X. (2017). Tracheostomy Among Infants With Hypoplastic Left Heart Syndrome Undergoing Cardiac Operations: A Multicenter Analysis. Ann Thorac Surg, 103(4), 1308-1314. doi:10.1016/j.athoracsur.2016.09.016
  • Rabie, N. Z., Sandlin, A. T., Barber, K. A., Ounpraseuth, S., Nembhard, W., Magann, E. F., & Lowery, C. (2017). Teleultrasound: How Accurate Are We? J Ultrasound Med, 36(11), 2329-2335. doi:10.1002/jum.14304
  • Shinkawa, T., Holloway, J., Tang, X., Gossett, J. M., & Imamura, M. (2017). A ferromagnetic surgical system reduces phrenic nerve injury in redo congenital cardiac surgery. Interact Cardiovasc Thorac Surg, 24(5), 802-803. doi:10.1093/icvts/ivw444
  • Shinkawa, T., Chipman, C., Holloway, J., Tang, X., Gossett, J. M., & Imamura, M. (2017). Single center experience of aortic bypass graft for aortic arch obstruction in children. Heart Vessels, 32(1), 76-82. doi:10.1007/s00380-016-0842-x
  • St Louis, A. M., Kim, K., Browne, M. L., Liu, G., Liberman, R. F., Nembhard, W. N., Kirby, R. S. (2017). Prevalence trends of selected major birth defects: A multi-state population-based retrospective study, United States, 1999 to 2007. Birth Defects Res, 109(18), 1442-1450. doi:10.1002/bdr2.1113
  • Stingone, J. A., Luben, T. J., Carmichael, S. L., Aylsworth, A. S., Botto, L. D., Correa, A., Olshan, A. F. (2017). Maternal Exposure to Nitrogen Dioxide, Intake of Methyl Nutrients, and Congenital Heart Defects in Offspring. Am J Epidemiol, 186(6), 719-729. doi:10.1093/aje/kwx139
  • Ailes, E. C., Gilboa, S. M., Gill, S. K., Broussard, C. S., Crider, K. S., Berry, R. J., Reefhuis, J. (2016). Association between antibiotic use among pregnant women with urinary tract infections in the first trimester and birth defects, National Birth Defects Prevention Study 1997 to 2011. Birth Defects Res A Clin Mol Teratol, 106(11), 940-949. doi:10.1002/bdra.23570
  • Dawson, A. L., Tinker, S. C., Jamieson, D. J., Hobbs, C. A., Berry, R. J., Rasmussen, S. A., Reefhuis, J. (2016). Twinning and major birth defects, National Birth Defects Prevention Study, 1997-2007. J Epidemiol Community Health, 70(11), 1114-1121. doi:10.1136/jech-2015-206302
  • Gilboa, S. M., Devine, O. J., Kucik, J. E., Oster, M. E., Riehle-Colarusso, T., Nembhard, W. N., Marelli, A. J. (2016). Congenital Heart Defects in the United States: Estimating the Magnitude of the Affected Population in 2010. Circulation, 134(2), 101-109. doi:10.1161/CIRCULATIONAHA.115.019307
  • Howley, M. M., Browne, M. L., Van Zutphen, A. R., Richardson, S. D., Blossom, S. J., Broussard, C. S., Druschel, C. M. (2016). Maternal autoimmune disease and birth defects in the National Birth Defects Prevention Study. Birth Defects Res A Clin Mol Teratol, 106(11), 950-962. doi:10.1002/bdra.23527
  • Jones, A. M., Isenburg, J., Salemi, J. L., Arnold, K. E., Mai, C. T., Aggarwal, D., Honein, M. A. (2016). Increasing Prevalence of Gastroschisis–14 States, 1995-2012. MMWR Morb Mortal Wkly Rep, 65(2), 23-26. doi:10.15585/mmwr.mm6502a2
  • Lara, D. A., Fixler, D. E., Ethen, M. K., Canfield, M. A., Nembhard, W. N., & Morris, S. A. (2016). Prenatal diagnosis, hospital characteristics, and mortality in transposition of the great arteries. Birth Defects Res A Clin Mol Teratol, 106(9), 739-748. doi:10.1002/bdra.23525
  • Li, M., Li, J., Wei, C., Lu, Q., Tang, X., Erickson, S. W., Hobbs, C. A. (2016). A Three-Way Interaction among Maternal and Fetal Variants Contributing to Congenital Heart Defects. Ann Hum Genet, 80(1), 20-31. doi:10.1111/ahg.12139
  • Li, M., Li, J., He, Z., Lu, Q., Witte, J. S., Macleod, S. L., Cleves, M. A. (2016). Testing Allele Transmission of an SNP Set Using a Family-Based Generalized Genetic Random Field Method. Genet Epidemiol, 40(4), 341-351. doi:10.1002/gepi.21970
  • Mulkey, S. B., Bai, S., Luo, C., Cleavenger, J. E., Gibson, N., Holland, G., Bhutta, A. T. (2016). School-Age Test Proficiency and Special Education After Congenital Heart Disease Surgery in Infancy. J Pediatr, 178, 47-54.e41. doi:10.1016/j.jpeds.2016.06.063
  • Nembhard, W. N., Bourke, J., Leonard, H., Eckersley, L., Li, J., & Bower, C. (2016). Twenty-five-year survival for aboriginal and caucasian children with congenital heart defects in Western Australia, 1980 to 2010. Birth Defects Res A Clin Mol Teratol, 106(12), 1016-1031. doi:10.1002/bdra.23572
  • Winston, J. J., Emch, M., Meyer, R. E., Langlois, P., Weyer, P., Mosley, B., Luben, T. J. (2016). Hypospadias and maternal exposure to atrazine via drinking water in the National Birth Defects Prevention study. Environ Health, 15(1), 76. doi:10.1186/s12940-016-0161-9
  • Dawson, A. L., Tinker, S. C., Jamieson, D. J., Hobbs, C. A., Rasmussen, S. A., & Reefhuis, J. (2015). Epidemiology of twinning in the National Birth Defects Prevention Study, 1997 to 2007. Birth Defects Res A Clin Mol Teratol, 103(2), 85-99. doi:10.1002/bdra.23325
  • de la Cruz, C. Z., Thompson, E. L., O’Rourke, K., & Nembhard, W. N. (2015). Cesarean section and the risk of emergency peripartum hysterectomy in high-income countries: a systematic review. Arch Gynecol Obstet, 292(6), 1201-1215. doi:10.1007/s00404-015-3790-2
  • Miquel-Verges, F., Mosley, B. S., Block, A. S., & Hobbs, C. A. (2015). A spectrum project: preterm birth and small-for-gestational age among infants with birth defects. J Perinatol, 35(3), 198-203. doi:10.1038/jp.2014.180
  • Reefhuis, J., Gilboa, S. M., Anderka, M., Browne, M. L., Feldkamp, M. L., Hobbs, C. A., Honein, M. A. (2015). The National Birth Defects Prevention Study: A review of the methods. Birth Defects Res A Clin Mol Teratol, 103(8), 656-669. doi:10.1002/bdra.23384
  • Simeone, R. M., Oster, M. E., Hobbs, C. A., Robbins, J. M., Thomas Collins, R., & Honein, M. A. (2015). Factors associated with inpatient hospitalizations among patients aged 1 to 64 years with congenital heart defects, Arkansas 2006 to 2011. Birth Defects Res A Clin Mol Teratol, 103(7), 589-596. doi:10.1002/bdra.23402
  • Simeone, R. M., Oster, M. E., Hobbs, C. A., Robbins, J. M., Collins, R. T., & Honein, M. A. (2015). Population-based study of hospital costs for hospitalizations of infants, children, and adults with a congenital heart defect, Arkansas 2006 to 2011. Birth Defects Res A Clin Mol Teratol, 103(9), 814-820. doi:10.1002/bdra.23379
  • Tang, X., Cleves, M. A., Nick, T. G., Li, M., MacLeod, S. L., Erickson, S. W., National Birth Defects Prevention, S. (2015). Obstructive heart defects associated with candidate genes, maternal obesity, and folic acid supplementation. Am J Med Genet A, 167(6), 1231-1242. doi:10.1002/ajmg.a.36867
  • Tang, X., Hobbs, C. A., Cleves, M. A., Erickson, S. W., MacLeod, S. L., & Malik, S. (2015). Genetic variation affects congenital heart defect susceptibility in offspring exposed to maternal tobacco use. Birth Defects Res A Clin Mol Teratol, 103(10), 834-842. doi:10.1002/bdra.23370
  • Tinker, S. C., Carmichael, S. L., Anderka, M., Browne, M. L., Caspers Conway, K. M., Meyer, R. E., Reefhuis, J. (2015). Next steps for birth defects research and prevention: The birth defects study to evaluate pregnancy exposures (BD-STEPS). Birth Defects Res A Clin Mol Teratol, 103(8), 733-740. doi:10.1002/bdra.23373
  • Wang, Y., Liu, G., Canfield, M. A., Mai, C. T., Gilboa, S. M., Meyer, R. E., Kirby, R. S. (2015). Racial/ethnic differences in survival of United States children with birth defects: a population-based study. J Pediatr, 166(4), 819-826.e811-812. doi:10.1016/j.jpeds.2014.12.025
  • Webber, D. M., MacLeod, S. L., Bamshad, M. J., Shaw, G. M., Finnell, R. H., Shete, S. S., Hobbs, C. (2015). Developments in our understanding of the genetic basis of birth defects. Birth Defects Res A Clin Mol Teratol, 103(8), 680-691. doi:10.1002/bdra.23385
  • Ailes, E. C., Gilboa, S. M., Riehle-Colarusso, T., Johnson, C. Y., Hobbs, C. A., Correa, A., National Birth Defects Prevention, S. (2014). Prenatal diagnosis of nonsyndromic congenital heart defects. Prenat Diagn, 34(3), 214-222. doi:10.1002/pd.4282
  • Collins, R. T., 2nd, Fram, R. Y., Tang, X., Robbins, J. M., & St John Sutton, M. (2014). Hospital utilization in adults with single ventricle congenital heart disease and cardiac arrhythmias. J Cardiovasc Electrophysiol, 25(2), 179-186. doi:10.1111/jce.12294
  • Dabit, J. Y., Romitti, P. A., Makelarski, J. A., Tyler, M. C., Damiano, P. C., Druschel, C. M., Burnett, W. B. (2014). Examination of mental health status and aggravation level among mothers of children with isolated oral clefts. Cleft Palate Craniofac J, 51(4), e80-87. doi:10.1597/12-298
  • Fixler, D. E., Xu, P., Nembhard, W. N., Ethen, M. K., & Canfield, M. A. (2014). Age at referral and mortality from critical congenital heart disease. Pediatrics, 134(1), e98-105. doi:10.1542/peds.2013-2895
  • Glidewell, J., Reefhuis, J., Rasmussen, S. A., Woomert, A., Hobbs, C., Romitti, P. A., & Crider, K. S. (2014). Factors affecting maternal participation in the genetic component of the National Birth Defects Prevention Study-United States, 1997-2007. Genet Med, 16(4), 329-337. doi:10.1038/gim.2013.143
  • Hobbs, C. A., Cleves, M. A., Macleod, S. L., Erickson, S. W., Tang, X., Li, J., Malik, S. (2014). Conotruncal heart defects and common variants in maternal and fetal genes in folate, homocysteine, and transsulfuration pathways. Birth Defects Res A Clin Mol Teratol, 100(2), 116-126. doi:10.1002/bdra.23225
  • Hobbs, C. A., Chowdhury, S., Cleves, M. A., Erickson, S., MacLeod, S. L., Shaw, G. M., Tycko, B. (2014). Genetic epidemiology and nonsyndromic structural birth defects: from candidate genes to epigenetics. JAMA Pediatr, 168(4), 371-377. doi:10.1001/jamapediatrics.2013.4858
  • Kucik, J. E., Nembhard, W. N., Donohue, P., Devine, O., Wang, Y., Minkovitz, C. S., & Burke, T. (2014). Community socioeconomic disadvantage and the survival of infants with congenital heart defects. Am J Public Health, 104(11), e150-157. doi:10.2105/ajph.2014.302099
  • Li, M., Cleves, M. A., Mallick, H., Erickson, S. W., Tang, X., Nick, T. G., Hobbs, C. A. (2014). A genetic association study detects haplotypes associated with obstructive heart defects. Hum Genet, 133(9), 1127-1138. doi:10.1007/s00439-014-1453-1
  • Li, M., Erickson, S. W., Hobbs, C. A., Li, J., Tang, X., Nick, T. G., Cleves, M. A. (2014). Detecting maternal-fetal genotype interactions associated with conotruncal heart defects: a haplotype-based analysis with penalized logistic regression. Genet Epidemiol, 38(3), 198-208. doi:10.1002/gepi.21793
  • Morris, S. A., Ethen, M. K., Penny, D. J., Canfield, M. A., Minard, C. G., Fixler, D. E., & Nembhard, W. N. (2014). Prenatal diagnosis, birth location, surgical center, and neonatal mortality in infants with hypoplastic left heart syndrome. Circulation, 129(3), 285-292. doi:10.1161/circulationaha.113.003711
  • Shaw, G. M., Yang, W., Carmichael, S. L., Vollset, S. E., Hobbs, C. A., Lammer, E. J., & Ueland, P. M. (2014). One-carbon metabolite levels in mid-pregnancy and risks of conotruncal heart defects. Birth Defects Res A Clin Mol Teratol, 100(2), 107-115. doi:10.1002/bdra.23224
  • Tang, X., Nick, T. G., Cleves, M. A., Erickson, S. W., Li, M., Li, J., Hobbs, C. A. (2014). Maternal obesity and tobacco use modify the impact of genetic variants on the occurrence of conotruncal heart defects. PLoS One, 9(9), e108903. doi:10.1371/journal.pone.0108903
  • Weedn, A. E., Mosley, B. S., Cleves, M. A., Waller, D. K., Canfield, M. A., Correa, A., & Hobbs, C. A. (2014). Maternal reporting of prenatal ultrasounds among women in the National Birth Defects Prevention Study. Birth Defects Res A Clin Mol Teratol, 100(1), 4-12. doi:10.1002/bdra.23178
  • Blossom, S. J., Rau, J. L., Best, T. H., Bornemeier, R. A., & Hobbs, C. A. (2013). Increased maternal cytokine production and congenital heart defects. J Reprod Immunol, 97(2), 204-210. doi:10.1016/j.jri.2012.12.004
  • Collins, R. T., 2nd, Fram, R. Y., Tang, X., Robbins, J. M., & Sutton, M. S. (2013). Impact of anatomical subtype and medical comorbidities on hospitalizations in adults with single ventricle congenital heart disease. Int J Cardiol, 168(5), 4596-4601. doi:10.1016/j.ijcard.2013.07.164
  • Hollis, N. D., Allen, E. G., Oliver, T. R., Tinker, S. W., Druschel, C., Hobbs, C. A., Bean, L. J. (2013). Preconception folic acid supplementation and risk for chromosome 21 nondisjunction: a report from the National Down Syndrome Project. Am J Med Genet A, 161a(3), 438-444. doi:10.1002/ajmg.a.35796
  • Hunter, J. E., Allen, E. G., Shin, M., Bean, L. J., Correa, A., Druschel, C., Sherman, S. L. (2013). The association of low socioeconomic status and the risk of having a child with Down syndrome: a report from the National Down Syndrome Project. Genet Med, 15(9), 698-705. doi:10.1038/gim.2013.34
  • Knecht, K. R., MacLeod, S. L., Hobbs, C. A., Li, M., & Morrow, W. R. (2013). Gene expression profiling in pediatric heart transplant rejection. Int J Cardiol, 168(5), 5052-5053. doi:10.1016/j.ijcard.2013.07.211
  • Nembhard, W. N., Xu, P., Ethen, M. K., Fixler, D. E., Salemi, J. L., & Canfield, M. A. (2013). Racial/ethnic disparities in timing of death during childhood among children with congenital heart defects. Birth Defects Res A Clin Mol Teratol, 97(10), 628-640. doi:10.1002/bdra.23169
  • O’Connor, M. J., Lind, C., Tang, X., Gossett, J., Weber, J., Monos, D., & Shaddy, R. E. (2013). Persistence of anti-human leukocyte antibodies in congenital heart disease late after surgery using allografts and whole blood. J Heart Lung Transplant, 32(4), 390-397. doi:10.1016/j.healun.2012.12.009
  • Sotres-Alvarez, D., Siega-Riz, A. M., Herring, A. H., Carmichael, S. L., Feldkamp, M. L., Hobbs, C. A., & Olshan, A. F. (2013). Maternal dietary patterns are associated with risk of neural tube and congenital heart defects. Am J Epidemiol, 177(11), 1279-1288. doi:10.1093/aje/kws349
  • Tyler, M. C., Wehby, G. L., Robbins, J. M., & Damiano, P. C. (2013). Separation anxiety in children ages 4 through 9 with oral clefts. Cleft Palate Craniofac J, 50(5), 520-527. doi:10.1597/11-239