September 5, 2017

Mitchell R. McGill, PhD

Mitchell McGill
Assistant Professor
 

Education

2017, Postdoctoral Fellowship, Washington University in St. Louis, Clinical chemistry and drug-induced liver disease
2013, PhD, University of Kansas, Toxicology
2007, BA, University of Missouri at Kansas City, Biology

Research Interests

  • Drug-induced liver injury
  • Biomarkers
  • Liver Regeneration
  • Clinical laboratory testing

Courses Taught

  • REGS 6013 FDA Regulations
  • ENVH 5202 Environmental Hazards Controls
  • ENVH 5221 Regulations in Environmental Health

Selected Recent Publications

Smith AK, Ropella GEP, McGill MR, Krishnan P, Dutta L, Kennedy RC, Jaeschke H, Hunt CA. (2019) Contrasting model mechanisms of ALT release from damaged and necrotic hepatocytes as an example of general biomarker mechanisms. PLoS Comput Biol.Submitted.

Vazquez JH, Clemens MM, Allard FD, Yee EU, Kennon-McGill S, Mackintosh SG, Jaeschke H, Hambuchen MD, McGill MR. (2019) Identification of serum biomarkers to distinguish hazardous and benign aminotransferase elevations. Toxicol Sci. [Epub ahead of print]

McCullough S, Dweep H, McGill MR, Bhattacharyya S, James L, Frankowski S, Woodall A, Kearns G, Gill P.(2019) Granzyme B and miR-378a Interaction in Acetaminophen Toxicity in Children.Microrna. [Epub ahead of print]

Clemens MM, Kennon-McGill S, Apte U, James LP, Finck BN, McGill MR. (2019) The inhibitor of glycerol-3-phosphate acyltransferase FSG67 blunts liver regeneration after acetaminophen overdose by altering GSK3β and β-catenin signaling. Food Chem Toxicol.125,279-288.

Kennedy RC, Smith AK, Ropella GEP, McGill MR, Jaeschke H, Hunt C. (2019) Propagation of pericentral necrosis during acetaminophen-induced liver injury: evidence for early interhepatocyte communication and information-exchange. Toxicol Sci. 169, 151-166.

https://www.ncbi.nlm.nih.gov/myncbi/10k4U8A4bmpAd/bibliography/public/